logo

UC San Diego Health Performs World’s First Personalized Spine Surgery with 3D-Printed Implant


Key Highlights :

UC San Diego Health performs the world's first 3D-printed customized spinal implant surgery.

Accuracy with AI-bot guided design and fit will enhance healing, minimize complications, and set a new standard for customized surgical procedures.


Key Background :

The UC San Diego Health accomplishment last year is pointing towards future neurosurgery and precision medicine. Surgeons conducted the first patient-specific anterior cervical spine surgery with a specially engineered implant in a single patient during July 2025. Rather than using the conventional method by implementing off-the-shelf devices, the new method engineered each feature of the device to the patient's anatomy and set a new level of precision for spine care.

The procedure started with high-definition imaging, taking detailed pictures of the spinal anatomy of the patient. The data was subsequently processed with artificial intelligence, allowing experts to create a patient-specific implant that included accurate models of the patient's body shape. The implant was subsequently printed 3D in medical-grade titanium, providing strength, durability, and biocompatibility. By creating an implant that replicates the patient to precision, the process avoided the majority of the limitations of traditional, off-the-shelf devices.

Anterior cervical fusion has been used for over a half-century to treat deformity, spinal stenosis, and disc degenerative disease. The procedure was successful, but conventional implants deform patients into the form of a foreign body. It can result in malalignment, prolonged recovery, or future revision surgery. Patient-specific implant prevents such side effects as it does not invade healthy tissue, enhances spinal alignment, and promotes quicker recovery. These patients undergoing the surgery are also likely to recover faster, feel less pain, and be more functional in the long term. Surgeons of the pioneering surgery believe that the discovery is merely the start of a revolution to overhaul surgery.

Dr. Joseph Osorio, the surgeon who conducted the procedure, said that each spine is as unique as a fingerprint, and this is a big affirmation of treatments being made to be directed at an individual. His UC San Diego Neurosurgery Chairman Dr. Alexander Khalessi contributed the innovation is taking personalized medicine to the field of spine surgery. They both explained that together, advanced imaging, AI, and 3D printing technologies have the potential to revolutionize volumes of care in every specialty of medicine. Spinal surgery, for example, has been hardly modified since the 1950s when anterior cervical fusion was common practice.

This new technology demonstrates, though, how technology can redefine even the most ordinary of norms. From "one-size-fits-all" to patient-specific implants per patient, UC San Diego Health is breaking into a trend that will take hold in orthopedic surgery. The future of the implant—for the back, the hip, or knee—is potentially fully customized, providing patients not only more effective treatment, but improved quality of life.


About the Author

Kevin Smith

Kevin Smith is a Managing Editor at World Care Magazine.